AntiDepressants medications can be ordered online
Life with antidepressant drugs
According to most psychiatrists, the leading treatment for depression is a therapy with psychopharmacological agents. It should be noted that antidepressants can also be effective in the treatment of anxiety, fear, compulsive disorders, migraine, vegetative crisis and they can even eliminate pain of different origins as antidepressants tend to increase the pain threshold.
Modern antidepressants are medicines that improve the condition of patients with depression, contributing to the reduction of affective, cognitive and motor manifestations of depression. They are usually classified according to the chemical structure and mechanism of action. The fastest way to get those drugs is to order antidepressants online.
Currently, there are several tens of commonly used basic antidepressants. At the same time those drugs are different by their effectiveness and impact, adverse reactions, and many other indicators. Buy cheap antidepressants online.
What diseases are treated with antidepressants?
One of the main indications for antidepressants is depression. The effectiveness of antidepressants in the symptomatic relief of depression was established half a century ago. Later, it was discovered that antidepressants are effective not only in treating depressive symptoms but also in the prevention of recurrent depressive episodes.
Selection of the most appropriate drug, selection of the optimal dose and duration of treatment depend on the characteristics of depression in each patient. Effect of antidepressants during depression never develops immediately. Although, improvement of individual manifestations of depressive state can be observed in the first days of treatment, the full therapeutic effect is achieved no earlier than after 4-6 weeks of therapy. Even in the complete elimination of all symptoms of depression the patient needs to continue taking the antidepressants for at least 6 months. This allows to fix the treatment effect and to prevent deterioration in the future.
Antidepressant drugs are also successfully used in the treatment of anxiety disorders, the main manifestations of which are phobias, panic attacks, obsessive thoughts and actions, the state of constant tension and heightened anxiety. The use of antidepressants in combination with psychotherapy is the most effective treatment for anxiety disorders.
Antidepressants are effective in the treatment of diseases characterized by the emergence of a variety of pain and discomfort in the body, fluctuations in blood pressure, heartbeat, dysfunction of the gastrointestinal tract, attacks of fever or chills, violations of bodily functions, as well as the change in the overall physical well-being with a sense of weakness, weakness, fatigue.
Groups of antidepressants and their effects
Antidepressants are heterogeneous in terms of their impact on the different forms of depression: apathy, anxiety or motor agitation.
The clinical classification of antidepressants includes:
– antidepressants with a weak effect. They relieve anxiety and moderate influence on the motor excitation;
– antidepressants with marked sedative effect. They relieve anxiety, but without noticeable effect on psychomotor agitation;
– antidepressants without express calming effect, but with the releasing effect on reducing psychomotor activity.
In other words, the specific effect of some antidepressants is mainly associated with mood improvement and sedation, the others with stimulating, activating motility action and the third with the effect that noticeably improves mood.
The basic antidepressants include drugs, whose action is caused by inhibition of monoamine capturing, which play the role of carriers neurotransmitters of the central nervous system, in particular, of norepinephrine and (or) serotonin. Comparative activity of antidepressants to block the capture of noradrenaline towards serotonin affects the spectrum of activity and side effects of these drugs.
SSRIs antidepressants usually prescribed to treat depression. SSRI antidepressants only affect serotonin and not other neurotransmitters. Those antidepressants have fewer side effects than other antidepressants. SNRI antidepressants act the same as SSRIs, by blocking the reabsorption of neurotransmitters in the brain. But they can provoke more side effects.
Monoamine oxidase inhibitors represent a special group of antidepressants. MAO inhibitors treat anxiety, depression and bipolar disorder by blocking enzymes which are responsible for breaking down the neurotransmitters. MAO inhibitors should be used with caution as they can interact with other drugs.
Another group of antidepressants includes tricyclic and tetracyclic antidepressants. Tricyclic antidepressants were discovered accidentally. One Swiss physician assign to his patients imipramine in the 50s. Those who received the drug felt great improvement in mood. And soon, scientists realized that they can eliminate depression with imipramine. The drug received the name - tricyclic because of its structure, which is based on the triple carbon ring. Tricyclic and tetracyclic antidepressants increase the amount of serotonin and norepinephrine in the brain. This leads to the mood enhance. But at the same time those drugs also affect other neurotransmitters provoking more side effects than newer antidepressants.
Possible side effects and contraindications during use of antidepressant drugs
The most common side effects during treatment with antidepressants include: restlessness, anxiety, insomnia, headaches, impaired visual acuity, allergic skin reactions. The most frequently mentioned contraindications for antidepressants include hypersensitivity to the drug, pregnancy and breastfeeding, epilepsy, kidney dysfunction.
Action of antidepressants
Due to pharmacokinetic properties the most antidepressants that affect serotonin metabolism are long-acting drugs. They are used in fixed doses. However, the rate of excretion of these agents has its features according to the age of patients and diseases of the internal organs. Thus, the period of excretion, increases slightly in elderly patients and patients with impaired liver function.
Clinical trials of selective serotonin reuptake inhibitors have demonstrated that they are an effective tool in the most depressed states, which include anxiety, insomnia, psychomotor agitation and confusion. Typical indications for the use of selective serotonin reuptake inhibitors are depression with anxiety and restlessness. Medical literature emphasizes sensitivity of vital violations to the action of these antidepressants. Several studies have described that patients with melancholy gave a good therapeutic response to the use of such drugs. Due to good tolerability of these drugs, they can be recommended for elderly people. In addition to the treatment of depression, the prolonged use of antidepressants can prevent attacks of depression. You can buy antidepressant drugs online to save money and time.
Antidepressants Generic drug vs Brand
Today, we can assert that the vast majority of cases of depression respond well to treatment. Effective treatment of depression consists of a combination of pharmacotherapy, psychotherapy, and, if necessary, other treatments. Thus, the main role in the treatment, of course, belongs to antidepressant drugs. Those medications were specifically designed to treat many different types of depression.
Depression is a painful condition characterized by depressed or sad mood, feelings of guilt and a decrease in mental activity, combined with movement disorders and dysfunction of the internal organs (loss of appetite, weight loss, constipation, changes in heart rate, etc.). According to the World Health Organization , about 5% of the world population is constantly suffer from depression, and 10% of people suffer from depression in a particular period of life. Mechanisms of depression are not fully elucidated. But we know that depressive states in our body decrease the content of neurotransmitters (serotonin and norepinephrine), and therefore, this reduces the activity of transmission of impulses in the synapses, where these mediators "work".
Antidepressants are drugs that reduce the manifestations of depression. They contribute to the accumulation of serotonin and noradrenaline in the central nervous system, either preventing reuptake of these neurotransmitters by presynaptic membrane or inhibiting their degradation in the synaptic cleft. Antidepressants improve mood, eliminate feeling of depression and physical retardation.
The contents of Generic antidepressants are utterly the same as those of the Brand drugs. This is the same preparations with the same components. The difference between generic and brand drugs is in their price and name. You can order Generic Anafranil, Generic Desyrel, Generic Lexapro, Generic Paxil and many other generic antidepressants online by good price!
Antidepressants are often used for severe depression, but they can also be helpful for some forms of mild depression. Antidepressants are not a cure, they only alleviate the symptoms of depression and help depressed people feel the way they felt before flowing into the depression. Antidepressants can also be helpful in treating alcoholism, drug addiction and in treatment of other disorders as anxiety disorders, mental disorders, such as schizophrenia, senile dementia, organic brain disease, pathological reactions to stressful factors, narcolepsy, etc. You can buy antidepressant drugs online and use them as prescribed.
When taken orally, antidepressants are rapidly absorbed and distributed throughout the body. About 50% of the administered dose is eliminated in the average for 2 days, mostly with the urine, the rest of the drug is associated with blood proteins and completely withdraws only after 2 weeks.
Antidepressants have such main types: serotonin and norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors, tricyclic and tetracyclic antidepressants, MAO inhibitors.
MAO inhibitors have a pronounced stimulating effect. They are effectively used in the treatment of patients with anxiety, phobias, panic disorders. However, at high dosages, they can cause undesirable side effects.
Tricyclic antidepressants are the drugs of the first generation. They have a good antidepressant effect with less frequency of side effects. Have a significant positive effect on psychomotor and somatic symptoms. Tricyclic antidepressants are effective in the presence of sleep disorders in patients. The main disadvantage is significant cardiotoxic effect when used in high doses. Tetracyclic antidepressants are second-generation antidepressants that provide good antidepressant effect at lower severity of side effects than in tricyclic antidepressants.
Selective inhibitors of neuronal uptake (serotonin and / or noradrenaline) belong to the third generation of antidepressants synthesized in recent years. They are characterized by good antidepressant action with minimal side effects. A significant advantage is a single dose of the drug per day. Action develops slowly.
Thus, Generic Remeron, Anafranil belong to tricyclic antidepressants, Generic Lexapro, Celex, Luvox belong to SSRI antidepressants, Generic Effexor belongs to SNRI antidepressants, Generic Risperdal, Wellbutrin, Zyprexa belong to atypical antipsychotic medications.
Today, number of antidepressants amounts to many tens. Antidepressants improve pathologically depressed mood, as well as the general condition of patients. Moreover, these drugs do not increase the normal mood and do not show psycho-stimulant effect. Some antidepressants have anti-anxiety, sedative, hypnotic properties.