Trivastal (Piribedil 50 mg)
Generic Trivastal (Piribedil 50 mg) guide:
What is Trivastal? When is this medication used?
Trivastal is a branded name of an antiparkinsonian medication Piribedil. This name is used in certain countries while in other countries the medication is sold under different names.
The indications for the medication use include Parkinson’s disease and some other conditions such as an additional symptomatic therapy in chronic violation of cognitive functions as a result of aging including attention and memory disorders; as an auxiliary symptomatic therapy for intermittent claudication due to obliterating diseases of arteries of the lower extremities; therapy of symptoms of eye diseases of ischemic nature including reduction of visual acuity, narrowing of the field of view, and reduction in the contrast of colors.
The effects of the preparation are caused by the stimulation of the dopamine receptors in the central nervous system and predominantly in the nuclei of the extrapyramidal system. The active substance, Piribedil, increases the blood inflow to the brain tissues, fills them with oxygen, and in general improves the brain metabolism. It also stimulates the transmission of the nerve impulses, enhances the electrical activity of cortical neurons, excites peripheral dopamine receptors in the smooth muscles of the vessels and has a vasodilating effect.
What is the medication sold as Generic Trivastal? Why is it so much cheaper than the branded medicine?
The active substance through which the effect of the branded medication Trivastal is achieved is no longer protected by the exclusive patent of its developer. It means that the same ingredient and formula can be used to synthesize the same medication by other pharmaceutical companies. These companies, however, have to name their medications differently. There are hundreds of names under which the same medication can be found but you don’t need to look for them if you want to buy Trivastal cheap. The cheaper versions of the medication are called Generic Trivastal or Generic Piribedil. These the terms used internationally. The term “generic” was introduced by the World Health Organization that also promotes and encourages the making of generics because they help to satisfy the world’s demand for the most efficient medicines and make them affordable for people from the developing countries. If you live in the U.S., for instance, you probably know that all medications there are quite expensive and not everyone can afford them which is why generics are also popular in the developed countries. Worth noting though, that they are much cheaper in the developing countries. You can also enjoy a lower price if you choose to buy Generic Trivastal from our online pharmacy. We operate from the country where this medication is sold much cheaper than in the U.S. and the UK and deliver the medication internationally.
If you wonder whether the generic has the same level of efficacy as the branded medication, the answer is “yes.” To be sure that you buy correct preparation, always check for the active substance which is written below the trade name on the box of pills and must be Piribedil. All medications based on this substance if it is indicated on the package before they are allowed onto the market, are strictly tested for efficacy and correspondence to the original formula. They are much cheaper not because they are inferior but because their manufacturers didn’t invest in the development of the medication and operate in the developing countries where all production costs are lower. Besides, they do not set the high prices because their main markets are also developing world where people wouldn’t be able to afford such expensive medications as in the U.S. or the UK.
When should I buy Piribedil?
You can without any doubts buy Generic Piribedil if your healthcare provider prescribes you Trivastal because the drugs are identical but the generic version costs several times cheaper. If you don’t have a prescription, you can still purchase the medication from our online pharmacy for the therapy of Parkinson’s disease, cognitive functions impairment such as memory and attention due to elderly age, intermittent claudication, eye diseases of ischemic nature including reduction of visual acuity, narrowing of the field of view, and reduction in the contrast of colors. But before you get the medication and start taking it, we strongly advise you to consult a specialist first. In some cases, the medication can be unsuitable for you or it will eliminate the symptoms while the cause could be treated but you neglect it minimizing the symptoms instead.
When shouldn’t I buy Generic Trivastal?
The preparation is contraindicated for people with the intolerance of the active substance or other ingredients of the medication, in arterial hypotension (low blood pressure), collapse, acute myocardial infarction, during pregnancy and breastfeeding.
If you are unsure whether you have any of these conditions or not, make sure to talk about it with your therapist before you buy Piribedil.
The preparation is also contraindicated to be combined with certain medicines and substances. You can find out more about it from our following section.
Interactions with other medications
If you use neuroleptics with pronounced antipsychotic properties (except for clozapine) and want to order Trivastal, you should consult your healthcare provider first as this combination of medicines is contraindicated.
The antagonists of dopamine including phenothiazines, butyrophenones, thioxanthenes, and metoclopramide taken along with Pribedil-based preparations can mutually decrease each others’ effectiveness.
The lowering of the medication effect can be also noticed in concurrent use of antiemetics (anti-vomit) of the group of dopamine antagonists.
In case you use any medications or supplements at the time you want to start using Generic Trivastal, it would be wise to inform your doctor about all of them and ask if their use isn’t contraindicated.
How to use Generic Trivastal?
The medication must be used absolutely in the same manner as the branded medication. If you have recommendations from your doctor, you should follow them.
In this section we provide the information on the regular dosage regimens and recommendations for use of the preparation without side effects.
The pills should be taken orally after meal. The daily dosage for cognitive functions impairment is from 50 mg taken once a day to 100 mg split into two intakes.
The treatment of Parkinson’s disease is made with 150-250 mg a day split into 3-5 intakes in monotherapy. If the medication is taken with Levodopa, the daily dosage is 100-150 mg a day split into 2-3 intakes.
In case you start suffering from indigestion as a side effect of the preparation, you can start taking antiemetics (anti-nausea medicines) which act on peripheral dopamine receptors (for instance, domperidone).
In case your doctor prescribes you to start taking neuroleptics, the dosages of Piribedil should be gradually lowered till the complete withdrawal because these medicines are incompatible. In sharp withdrawal there is a risk of malignant neuroleptic syndrome development.
If order Generic Trivastal and start using it but the medication use causes unbearable sleepiness or even sudden falling asleep, you should consult your doctor about the dosage lowering or the withdrawal of the medication. This symptom is a serious one as it can contribute to falling caused either by falling asleep or blood pressure lowering which is especially dangerous for elderly patients.
In general, during the therapy with the medication it is advised to avoid driving vehicles or engaging in any activity that requires extreme focus and attention.
Possible adverse reactions of Generic Trivastal use
Some of the possible adverse reactions are described in the previous section and there you can also find the measures how to cope with them. The most common adverse reactions are nausea, sleepiness, sudden falling asleep, low blood pressure, confusion, hypersexuality, increased libido, gambling, compulsive overeating, obsessive wish to make purchases, and so on. In occurrence of these symptoms you should immediately contact the doctor and discuss the lowering of the dosage or the discontinuation of the therapy. Considering that these behavioral changes can be unnoticed by the patient, he or she should inform the relatives, family members or nurses about such possible negative reactions and tell them to address a doctor in case of their occurrence.
The main symptom of an overdose with Piribedil is vomiting. You should seek medical assistance in case you have this symptom as you would need gastric lavage and symptomatic therapy.
Where to buy Trivastal?
The best option to save on the pills themselves and the prescription is to order Piribedil from our online drugstore. We sell the medication over-the-counter, at an attractive price, and frequently have special discounts and offers.
Shipping of Trivastal
We will ship your order to any corner of the world and will provide you with the tracking number.
Our doctor prescribes Piribedil online for free, and there is no doctor’s consultation fee.
All orders of Piribedil arrive in discrete unmarked parcels. We leave the shipment description blank.