Symbicort (Budesonide 6/100 mcg)
More facts about Generic Symbicort (Budesonide 6/100 mcg):
Generic Symbicort (Budesonide 6/100 mcg) guide:
What is the medication sold under the trade name Symbicort?
Symbicort is a brand of anti-asthmatic combination inhaler registered by the pharmaceutical company AstraZeneca. The inhaler is based on two active agents Budesonide and Formoterol. These two substances are used also separately but in a combined formulation they enhance the effect of each other and can render a more potent and prolonged effect. If your healthcare provider advises you to buy Symbicort, you can look for a generic version of the medication instead because the exclusive right of the formula developer is no longer in action and other pharmaceutical firms are able to use the same formula but under a different name.
Symbicort and its generics are combined bronchodilator medications that contain glucocorticosteroid for local application and selective beta 2-adrenic receptors stimulator that render an additive effect in lowering of the frequency of exacerbations of bronchial asthma.
Budesonide is an inhalable glucocorticosteroid that when used in the recommended dosages, renders an anti-inflammatory effect and provokes fewer adverse effects than the glucocorticosteroids taken by mouth.
Formoterol is a selective beta 2-adrenic stimulator that causes the relaxation of the smooth muscles in the bronchi in individuals with reversible obstruction of the respiratory ways.
The bronchodilator effect of the preparation occurs quite fast, within one-three minutes after the inhalation of one dose and maintains for twelve hours. The addition of Formoterol to Budesonide contributes to the lowered intensity of bronchial asthma symptoms, improves the function of bronchi, and reduces the periodicity of the disease outbreaks.
The effect of the combined medication on bronchial function is similar to that of a concurrent use of mono preparations of Budesonide and Formoterol. The medication is in general well tolerated.
When inhaled, Budesonide is quickly absorbed in the body. The max concentration is achieved in thirty minutes. The concentration of the medication in the body after an inhalation is 32-44%. The volume in the systemic circulation is 49%.
When inhaled, Formoterol is absorbed even faster, the max concentration of it within the body is observed only ten minutes after an inhalation. The concentration of the substance in the lungs after an inhalation is 28-49% of the received dosage. The systemic circulation of the medication is 61% from the received dosage.
It is the first combination inhaler that is effective both in the prevention of asthma attacks (bronchospasm) and stopping of an onset of an acute bronchospasm.
What is the medication sold as Generic Symbicort?
Generic Symbicort is a collective term for all medications that have the same formula and composition as the branded drug Symbicort but are made by other drug making companies. This is possible because the developer of the medication has already lost the exclusive right to use the formula. The generics are usually cheaper than the branded medications for several reasons such as that their manufacturers didn’t develop the medicine by themselves; they save on advertising and production mostly marketing its medications in the developing countries. This practice is promoted by the World Health Organization as it balances the possibilities to obtain effective treatment for people from the developed and developing countries. However, the generics gain more and more popularity in the developed world too because all medications there are highly and unreasonably overpriced. The medication you can obtain when you buy Generic Symbicort from this webpage is absolutely the same as the branded medication but is several times cheaper which can allow you greatly save on the therapy without compromising the quality of it.
When should you purchase Generic Symbicort?
The best time to obtain the medication is when your therapist tells you that you need this medication exactly and consults you how and for how long you should use it. The indications for the medication use are bronchial asthma that is insufficiently controlled by the inhalation glucocorticoids and short-acting beta 2- adrenergic receptors stimulants or in an adequately controlled asthma with inhalation glucocorticoids and long-acting beta 2- adrenergic receptors stimulants. Besides, the medication is approved for the reduction of symptoms of obstructive pulmonary disease in some countries. You need to consult your doctor if he or she doesn’t prescribe you the medication but you want to buy Budesonide/Formoterol inhaler for the management of your condition to be sure that it would be suitable for you and that you don’t take any medications that will interfere with its action.
When shouldn’t you order Generic Symbicort?
The medication is contraindicated for people who are allergic to Budesonide, Formoterol, are lactose intolerant, and for children who hadn’t reached the age of six years.
The inhaler must be cautiously used in pregnant or breastfeeding women, in people with lung tuberculosis, in viral, fungal, or bacterial infections of the respiratory tract, in thyrotoxicosis, pheochromocytoma, diabetes, uncontrolled hypokalemia, severe arterial hypertension, aneurysm, tachyarrhythmia, long QT interval, and ischemic or any other heart disease.
If you have any chronic conditions or already use medications for asthma, make sure to inform your healthcare provider even if you don’t see any of these conditions or medicines in the list of contraindications.
What adverse effects can you anticipate from Generic Symbicort use?
Any medication can contribute to the development of negative effects especially if it is a combination medication such as Symbicort. If you buy Generic Budesonide/Formoterol for the first time, you can discover that the medication is unsuitable for you if you develop allergic reactions such as bronchospasm, skin rash, urticaria, itching, and swelling of the tongue or face. If you have these symptoms – notify your physician immediately and stop using the inhaler.
Other adverse effects include headache, tachycardia, tremor, candidiasis and irritation of the mucous membrane of the oropharynx, coughing, hoarseness, muscle cramps, agitation, nervousness, nausea, lightheadedness, and sleep violation, depressive mood, conduct disorder, slow growth in kids and teenagers, lowering of bone mineral density, cataracts and elevated intraocular pressure, hypersensitivity reactions of immediate or delayed types, the appearance of bruising, angina, hyperglycemia, changes in taste, labile arterial pressure, paradoxical bronchospasm, arrhythmia, and other heart-related symptoms.
Overdose signs and therapy
In case you inhaled more active substances than recommended, you can start suffering from tremor, lowering of the arterial pressure, metabolic acidosis, low potassium level, and high blood sugar. In prolonged intake of excessive doses, the systemic negative reactions such as Cushing's syndrome and suppression of adrenal function can develop.
The treatment includes symptomatic measures, i.e. measures aimed to reduce the symptoms.
What drug combinations should you avoid when using Budesonide/Formoterol?
Before you order Symbicort, make sure to talk with your physician about all medicines that you use or plan to use when you start the therapy with the inhaler.
Ketoconazole and other inhibitors of CYP3A4 enzyme raise the concentration of Budesonide in the body and respectively the likelihood of adverse effects development.
The action of Formoterol is reduced by the use of blockers of beta-adrenergic receptors.
The risk of negative reactions that concern heart and elongate the QT interval increases in the concurrent use of the inhaler with quinidine, disopyramide, some antihistamine preparations, dopamine, levothyroxine sodium, oxytocin, ethanol, furazolidone, procarbazine MAO inhibitors, tricyclic antidepressants, halogenated hydrocarbon anesthetic medicines, and some other preparations.
Other beta- adrenergic receptors stimulants enhance the potency of Formoterol adverse effects.
The derivatives of xanthine, some diuretics, and cardiac glycosides combined with Symbicort can increase the risk of hypokalemia.
How to use Budesonide/Formoterol inhaler?
Before you order Generic Symbicort, you should get an instruction of your healthcare provider on how to use the inhaler. The dosages are selected individually and depend on the severity of the condition.
Adults and kids older than six years using the inhaler with the dose of the active substances 80 mcg/4.5 mcg/dose should make one-two inhalations a day.
Adults and kids older than twelve years using the inhaler with the dose of the active substances 160 mcg/4.5 mcg/dose should make 1-2 inhalations a day.
Once the target control of symptoms is achieved, the dosage is advised be lowered to the minimum effective one.
Where to buy Symbicort?
You can purchase the branded medication at virtually any pharmacy but if you want to save on the therapy while getting the same effect, you should order Budesonide/Formoterol from our online pharmacy.
Shipping of Symbicort
Rxshop.md will ship your order to any corner of the world within 7-25 days based on the type of delivery you select.
Our doctor prescribes Budesonide online for free, and there is no doctor’s consultation fee.
All orders of Budesonide arrive in discrete unmarked parcels. We leave the shipment description blank.