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Generic Acuitel (Quinapril 5 mg) guide:
Generic Acuitel (Quinapril) is a medication used to treat hypertension or elevated blood pressure and congestive heart failure. The drug can be used as a single means to cope with high blood pressure or in combination with diuretics.
When should the drug be used?
The medication is indicated for people with high blood pressure, a medical condition that is diagnosed based on the daily measurements of arterial pressure. For different age and conditions, the normal blood pressure is different so you have to check with your doctor if you actually need the medication to lower the blood pressure or not before you buy Generic Acuitel (Quinapril).
The medication is also prescribed for congestive heart failure, the condition in which the heart is not pumping enough blood through the body and is unable to provide sufficient blood flow to the body organs. The condition can develop as a result of hypertension, heart overload, insufficient blood inflow to the heart due to myocardial infarction, myocarditis, toxic exposure (for instance, in Grave's disease), and so on.
What is the mechanism of action of Acuitel (Quinapril)?
All drugs based on the active substance called Quinapril, including the brand-name medications and generics, are prodrugs, i.e. they are transformed into an active substance only when entering the body. The medications inhibit the natural enzyme that is responsible for angiotensin II, a potent substance that contributes to the constriction of blood vessels which leads to the elevated blood pressure, formation from angiotensin I peptide hormone.
Besides the blood pressure lowering effect, because of the decreased angiotensin release, high amounts of sodium are excreted in urine. The medication also causes elevated levels of potassium in the blood.
How to use the drug?
First of all, before you buy Quinapril or Generic Acuitel, you should consult your doctor or at least have a precise diagnosis to be sure that you need the medication with the effect it provides. Besides, you should check if the medication is not contraindicated for you and that you don’t take any other medications that are incompatible with the drug. You can find all necessary information below.
For hypertension, as a monotherapy (when no other drugs such as diuretics are used), the daily dosage of Generic Acuitel is 10-20 mg taken once a day or divided into two intakes. Depending on the effectiveness of the drug in a certain patient, the daily dosage can be increased to 40-80 mg a day. The dosage adjustment should be made not sooner than after 2-4 weeks after the treatment start. The maximum daily dosage is 80 mg. In order to control the blood pressure dynamics, patients should measure it once a day.
If your doctor prescribes you diuretics along with Quinapril (Generic Acuitel), you should start taking the drug by 5 mg a day and adjust the dosage only under your doctor’s supervision.
The recommended starting dosage for people with congestive heart failure is 5 mg once a day or two times a day. In case the drug is tolerated well, the dosage can be gradually increased: first to 10 mg, then 20 mg, and up to 40 mg. The dosages higher than 5 mg should be divided into two intakes a day.
People with reduced kidney function should take lower dosages of the drug. The recommended dosage for patients with creatinine clearance more than 30 ml per minute is 5 mg. People with creatinine clearance below 30 ml per minute should take 2.5 mg a day. If the dosage is tolerated well, it can be increased every week gradually based on the clinical and hemodynamic effects.
Whom the drug is contraindicated?
Generic Acuitel (Quinapril) is contraindicated for people who have allergy or are hypersensitive to one or several components of the drug, pregnant women, children, people with severe liver and kidney insufficiency, and people who have had angioedema caused by other medications that inhibit angiotensin-converting enzyme.
What side effects can Acuitel (Quinapril) cause?
During the tests of the medication, it was proven that it rarely causes any side effects. The most frequent ones were: headaches (7.2%), dizziness (5.5%), coughing (3.9%), tiredness (3.5%), nasal congestion (3.2%), and nausea or vomiting (2.8%).
The rarest adverse reactions that were documented are: rapid heart rate, tachycardia, flatulence, dry mouth, pancreatitis, vertigo, nervousness, depression, somnolence, itching, increased sweating, rash, urinary tract infections, erectile dysfunction, and swelling.
With what medications the drug should not be combined?
When along with Acuitel (Quinapril) Tetracycline is used, the absorption of the latter drug is reduced by 28-40%.
Medications based on Lithium combined with the blood pressure medication and especially if it is used along with diuretics, cause increased levels of lithium in blood plasma and can result lithium toxicity.
When the drug is combined with nonsteroidal anti-inflammatory drugs, the therapeutic effect of the first medication can be reduced. If the patient who uses the drugs has kidney insufficiency, the combination of the medications can worsen the condition.
Generic Acuitel (Quinapril) and other medications from the group can increase the sensitivity to insulin which can result in hypoglycemia in patients with diabetes who use insulin or oral hypoglycemic drugs.
What should you do in the overdose with Acuitel (Quinapril)?
The symptoms of the overdose include the symptoms of severe hypotension (extremely lowered blood pressure) such as dizziness, fainting, blurred vision, nausea, rapid and shallow breathing, general weakness, and so on. The symptoms are treated with intravenous infusion of plasma-substituting solutions and other symptomatic measures.
Is there a difference between the brand-name drug and the generic?
No, there is no difference in the effect of the brand-name medication and generics. They have the identical composition and are based on the same formula. Generic drugs are cheaper because they are made by pharmaceutical companies that didn’t develop the drug but are able to use the formula due to legislation norms that oblige the developer to share the formula or bough the formula.
Where to buy Acuitel (Quinapril)?
If you have a prescription from your doctor, you can ask for Quinapril or its generics at your local drugstores. If you want to save and do not go to your doctor every time you need a refill, you can purchase the medication from our online drugstore. We sell the drug without a prescription as we operate from the country where the drug is sold over-the-counter. Moreover, we are able to sell the medication cheaper because we do not operate in the U.S. where it is extremely expensive to run a pharmacy even an online one.
Generic Acuitel (Quinapril) shipping by Rxshop
If you buy medications from our online drugstore for $170 or more in total, we will ship the drugs at our expense. If your order is less than that, you can opt for a standard or express shipping for which you have to pay additionally. Nevertheless, even paying for the shipping you will greatly save compared to what you would have paid at your local drugstores.
We have shipping facilities in the South Pacific, Europe and the Asia. Standard shipping usually takes from 14 to 25 days. Express shipping takes from 7 to 12 days. If you choose express shipping, you will get a tracking number so you can check your parcel status every day. In standard shipping the tracking is unavailable.
Our doctor prescribes Quinapril online for free, and there is no doctor’s consultation fee.
All orders of Quinapril arrive in discrete unmarked parcels. We leave the shipment description blank.