Crestor (Rosuvastatin 5 mg)
More facts about Generic Crestor (Rosuvastatin 5 mg):
Generic Crestor (Rosuvastatin 5 mg) guide:
What is the medication called Crestor?
Crestor is a trade name owned by the Japanese pharmaceutical company Shionogi. The company developed the active substance for the medication and named it Rosuvastatin in 2003. The trade name was invented later and registered for the sole use by the company, though the formula can be used by other pharmaceutical firms too. The medication is used to prevent various heart diseases and complications of heart diseases caused by high “bad” cholesterol levels. In the use of the preparation, the lowering of low-density lipoprotein and very low-density lipoprotein (cholesterol) levels are observed. It contributes to the lowering of overall cholesterol and triglycerides levels and the increase of the level of high-density lipoprotein (cholesterol). Besides, people who use the preparation are reported to enjoy the lowering of apolipoprotein B and an increase in the level of apolipoprotein A.
The therapeutic effect of the medication use is developed within the first week after the therapy start. The maximum efficiency can be observed and assessed within two weeks of the medication use. The maximum effect is usually maintained after the two weeks of use and throughout the whole treatment course.
The effect of the preparation is achieved because it is a selective inhibitor of a reductase that converts certain coenzyme into mevalonic acid, a precursor of sterols, including cholesterol. The preparation increases the amount of liver receptors of cholesterol of low density at the top of the cells thus enhancing the seizure and catabolism of low density lipoproteins and suppresses the synthesis of very low density lipoproteins in the liver. It reduces the size of the atherosclerotic plaque and increases the lumen of the vessels and the level of C-reactive protein.
Although the medication is very effective and innovative, it is advised to buy Crestor and start using it only if other measures to lower the level of cholesterol such as diet and exercising had not improved the level of cholesterol to a sufficient degree.
What is the medication sold as Generic Crestor? Why is it cheaper?
The medication you can find as Generic Crestor is basically the same drug as the branded medication but manufactured by another drug-making firm. It is possible because the patent for the exclusive use of the active substance of Crestor, Rosuvastatin, had already expired. It allows other companies to use the formula and make the same meds but under other names.
This practice is absolutely legal. Moreover, it is even promoted by the World Health Organization as it allows people to choose the manufacturers when they but the medicines they need based on the price per pill, for instance. The generics initially had been mainly developed and produced to satisfy the demand for the medications in the developing countries. As you may know, the majority of the new medications are invented in the developed countries where millions and even billions are spent on research. But the prices of the medications are so high that people from the developing countries wouldn’t be able to use these medicines if there were no generic versions of them. Moreover, even if enormous money is spent on the research, it still doesn’t justify the fact that the medicines are so expensive. Many manufacturers set unreasonably high prices for the medicines with the intentions of insurance companies to cover the cost of the treatment. But what should people who don’t have insurance do? The best option for them is to buy Generic Crestor or the generic of any other medication they need. The unreasonably high prices of the branded medicines make generics very popular not only in the developing but also developed countries.
You don’t need to worry about the efficiency of the generic when you buy it from Rxshop.md We sell only the best quality generic medicines from reputable drug manufacturers who before their meds are released onto the market get them properly tested and certified.
When should you buy Generic Crestor?
The preparation can be appointed for the therapy of adults and children older than ten years for hyperlipidemia, i.e. abnormally elevated levels of lipids and/or lipoproteins in the human blood. The medication should be used as an addition to the special diet and exercise.
Besides, you can buy Rosuvastatin for the prophylaxis of cardiovascular disorders and diseases if you are in a high-risk group, for instance, have a history of ischemic heart diseases in your family, are a smoker, suffer from diabetes type 2, have excessive body mass, or are older than 60 years of age and ever suffered from any cardiovascular disorder or elevated arterial tension.
If you have any of the conditions in which the medication should be used, we still advise you to consult your physician about the possibility to use the medication even though you can get it without a prescription from our online pharmacy to be sure that you won’t harm your health with its use.
When shouldn’t you buy Crestor or a generic version of the medicine?
There are many cases in which the use of the preparation is prohibited. Therefore, you must consult your doctor and undergo all necessary tests and checkups to be sure that the medication won’t be harmful to you.
The pills should not be taken by the people, who are hypersensitive, e.g. allergic to the active or additional substances of the pills including lactose.
The preparation is contraindicated for people with active liver diseases and/or kidney diseases when the creatinine clearance is lower than 30 milliliters per minute.
Pregnant and breastfeeding women must not use the pills.
The medication should be carefully used in people with myopathy.
The dosage of 40 mg a day or higher is prohibited to be used in people with any kidney dysfunction, any muscle disorders including family history, hypothyroidism, muscle toxicity caused by HMGCR inhibitors in history, chronic alcoholism, in the use of fibrates, a condition in which an increase in the level of Rosuvastatin in the serum is possible. This dosage is also unsuitable for people of Mongoloid race due to certain genetic contraindications.
You can buy Generic Rosuvastatin for your child only after consulting a pediatrician. For children, the medication can be used only in certain groups of them, i.e. older than 10 years in case a girl is having her period for a year or a boy who reached Tanner scale stage II development.
Given the risk of rhabdomyolysis (severe muscle disorder) and kidney failure, Rosuvastatin use should be made with extreme caution in patients with the following conditions: arterial hypotension, sepsis, injuries, disturbances in metabolic processes, after significant surgical interventions, uncontrolled epilepsy, violation of water-electrolyte balance, and endocrine disorders.
On top of that, the preparation is contraindicated or not recommended to be combined with other medicines. Find out more about it from the following section.
Interactions with other substances
It is contraindicated to use the medication along with cyclosporine and fibrates. Other undesirable combinations of Generic Crestor are with anticoagulants, H2-antihistamines, immunosuppressants, antifungal medications, additional lipid-lowering drugs, nicotinic acid preparations, HIV-protease inhibitors, diuretics, antacids, cardiac glycosides, and others.
When using the medication, it is advised to limit alcohol consumption to avoid damaging the liver.
If you take any medications or supplements and are not sure whether they are compatible with Generic Crestor, make sure to inform your doctor and get a proper consultation before you order Crestor and start taking the pills.
Adverse effects Rosuvastatin can be a cause of
When you start taking the pills, you should take into account the risk of development of certain side effects one of which is dizziness. Therefore, for the first days of the therapy, while you are getting used to the pills ‘effect, it is advised to avoid driving.
Other possible adverse reactions are hyperglycemia, diabetes mellitus, fatigue, headache, abdominal pain, nausea, constipation, muscle pain, myopathy, rhabdomyolysis, and the dose-dependent appearance of protein in the urine, Quincke's edema, skin allergic reactions, and others.
If you have any of these or other adverse effects, make sure to inform your doctor right away.
How Generic Crestor should be taken?
First of all, when you order Generic Crestor after your doctor appointed you the therapy with the branded medicine, you should follow his or her indications without any changes regardless of the trade name on the package as long as the active substance is Rosuvastatin.
The general instruction for the medication provides the following information on the dosage and regimen of use:
The pills are taken orally without regard to meals. Before the therapy is started, it is important to try other measures to reduce the level of cholesterol such as low-fat diet, exercising, and losing of excessive weight. The therapy with the medication is recommended only in the cases when the effect of non-drug methods is insufficient.
The dosage is selected individually in the range from 5 to 40 mg daily based on the efficiency and patient’s response to the therapy.
For the treatment of hypercholesterolemia, the starting dosage for patients who hadn’t received satins or used HMGCR inhibitors is from 5 to 10 mg a day. After four weeks of the therapy, the dosage can be increased gradually to 40 mg a day but not more. Besides, it is important to remember that the higher dosages are usually correlated with the increased likelihood of adverse reactions. It is recommended to stick to 20 mg a day and use the highest dosage only in severe cases and under a doctor’s supervision.
The prophylaxis of cardiovascular diseases in adults is usually made with 20 mg a day. Elderly patients are advised to start the therapy with 5 mg a day. The increase of the dosage is possible only in good tolerance of the medication and positive response to the therapy.
For children, the medication is used strictly under a control of a specialist and only if they hit the certain stage of puberty. The average dosage for children is 5 mg a day. If necessary, a doctor can appoint an increase of the dosage to up to 20 mg a day. The higher doses are not used in pediatrics.
People with impaired kidney function need dosage adjustments based on the creatinine clearance indicators: in cc less than 60 ml per minute, the starting dosage is 5 mg a day and the maximum dosage is 20 mg a day; in cc lower than 30 ml per minute, the medication is prohibited to be used.
People with liver function impairment need the assessment of their condition before the therapy start to choose the correct dosages. In an active or severe liver disorder the use of the medication is contraindicated.
People who suffer from myopathy should start the treatment with the dosage of 5 mg a day. The maximum dose for this group of patients is 20 mg a day.
Before you order Rosuvastatin and start taking the pills, make sure to get properly tested and consult a qualified specialist.
In case of an overdose of Rosuvastatin, symptomatic agents are used and supportive therapy is indicated if necessary.
In the case of an overdose of the drug Rosuvastatin, it is necessary to monitor the kidney and liver function.
Where to buy Crestor?
The best way to save on the treatment without compromising its quality is to order Generic Rosuvastatin from our online pharmacy.
We will deliver your order to any country and city of the world.
Our doctor prescribes Rosuvastatin online for free, and there is no doctor’s consultation fee.
All orders of Rosuvastatin arrive in discrete unmarked parcels. We leave the shipment description blank.