Lopid (Gemfibrozil 300 mg)
Generic Lopid (Gemfibrozil 300 mg) guide:
What is Lopid?
The substance on which the branded medication Lopid is based, Gemfibrozil, was developed in the late 1970s. The brand name was registered by the company who developed the medication able to lower the level of cholesterol and couldn’t be used by other drug-making companies. However, the exclusive right to use the formula for the production of medicines based on Gemfibrozil had already expired and other producers are able to make the same medicines and sell them but under different names.
The active ingredient was obtained as a result of research aimed to find the derivatives of Clofibrate that would have lower toxicity. Gemfibrozil turned out to be much less toxic but very effective hypolipidemic medication (reducing the lipid content in the blood). It reduces the content of VLDL (very low-density lipoproteins) in the blood of patients with hypertriglyceridemia (high triglycerides in the blood) that do not respond to ??? treatment with diet and other lipid-lowering drugs. Besides, the medication also increases the content of high-density lipoproteins (“good” cholesterol), suppresses peripheral lipolysis, and increases the excretion of free fatty acids from the liver, thereby reducing the synthesis of triglycerides in the liver, lowers the inclusion of long-chain fatty acids in newly synthesized triglycerides, accelerates the turnover and removal of cholesterol from the liver and increases its excretion with bile.
The effect of the medication can be observed only two-five days after the therapy start and is maximally developed within four weeks.
The mediation is quickly and well absorbed while taken orally. The maximum concentration after a single dose intake is developed within one and a half hours and after the use of several doses even faster – in an hour and twenty minutes. The medication is mostly excreted in urine and a low amount is excreted in bile.
Although it is a very effective and relatively safe medication, you should necessarily consult your doctor and try lowering the level of “bad” cholesterol by diet and physical activity and buy Lopid only if the desired lowering of the cholesterol is not achieved with non-pill measures.
What is the difference between Lopid and its generic versions?
Every year, more and more people opt for generic medications instead of the branded ones because they are cheaper but have the same effect. It is possible to get the same medications at a lower price because the exclusive patents of the formula developers expire which makes it possible for other drug makers to produce the same medicines using the formula. This practice is encourage and supported by the World Health Organization as it makes the vital and modern medications attainable for wider populations.
Many medications, especially the ones developed in the U.S., are highly overpriced for no reason. Yes, their developers spend a lot of money on the research yet they still are able to set 2-5 time lower prices for their medications and still gain profit. These ridiculously high prices make it possible to get the necessary medications only for people who have insurance. Other people either have to opt for inferior, old medications or, fortunately, get the same medications but under different names. If your doctor prescribes you Lopid but you don’t have enough money to undergo the complete treatment course with the branded medication, you can buy Generic Lopid instead. It is identical medication, based on the same formula and ingredients but sold cheaper because it is made by another company. Generic Lopid is not an officially registered name. It is a term used to make it easier for you to find the drug knowing only its branded name but you should not be turned off by the other name on the box of pills as long as the active substance of the tablets is Gemfibrozil.
When is it time to buy Generic Lopid?
The preparation is appointed for the therapy of hypertriglyceridemia in resistance to a curative diet and other lipid-lowering drugs.
In hyperchylomicronemia, i.e. the high content of neutral fat in the blood due to familial deficiency of lipoprotein lipase (an enzyme that destroys lipoproteins), the drug is less effective but since it is better tolerated than other medications in some patients, it can be still used.
The medications to lower the level of “unhealthy” cholesterol are used also to prevent heart diseases and their complications in people who have the high risk of their development but please consult a specialist before you buy Gemfibrozil for this purpose as it is not the first medication of choice. You can look through our range of medicines to lower the level of cholesterol to find the optimal solution in this section of our website.
When it’s not allowed to use Lopid?
Even if you have indications for the preparation use, it can be still prohibited to you while you are pregnant or breastfeeding, if you are allergic or hypersensitive to the medication, if you have severe violation of liver or kidney function.
The medication is also contraindicated for children and should be cautiously used in adults with hypertriglyceridemia, hepatic insufficiency, cholelithiasis, chronic cholecystitis (inflammation of the gallbladder), and severe chronic renal failure.
Besides, you should not buy Generic Gemfibrozil and use it with certain medications as the risk of the negative impact on the health increases.
Concurrent use of Lopid with other substances
Prior to starting the therapy with this preparation you need to check with your doctor that you don’t use any medications or substances that are incompatible with Generic Lopid such as Lovastatin (there is a possibility of the occurrence of severe myopathy and acute renal failure) and others.
The preparation lowers the effects of ursodeoxycholic and chenodeoxycholic acids due to increased cholesterol excretion in bile.
Lopid and its generics enhance the effects of indirect anticoagulants, oral hypoglycemic drugs (sulfonylurea derivatives).
The risk of lipids metabolism violation exists in the concurrent use of Lopid with oral contraceptives (birth control pills).
Possible adverse effects from the use of Generic Lopid pills
Gemfibrozil is usually well tolerated but certain adverse effects still can develop such as gastrointestinal disorders (abdominal pain, nausea, diarrhea); in rare cases, anemia (a decrease in hemoglobin in the blood), leukopenia (a decrease in the level of leukocytes in the blood), dizziness, headache, excessive fatigue, syncope, paresthesia, drowsiness, depression, lowered libido, erectile dysfunction, allergic reactions, and others.
Like Clofibrate which derivative it is, it can promote the formation of gallstones.
If after you order Lopid and start taking it you develop any negative symptoms, inform your healthcare provider immediately.
How to take Generic Lopid pills?
Before you order Generic Lopid, make sure to get a comprehensive consultation of your doctor who knows your health history and can respectively adjust the dosage and give individual recommendations on the therapy. It doesn’t matter if you buy a branded medication or a generic - the dosages are the same and you should take the pills in the same manner.
The regularly appointed dosages are 300-450 mg taken twice a day thirty minutes before breakfast and thirty minutes before dinner. The complete expected effect of the medication is developed within three-four weeks of uninterrupted use.
Please note that these dosages are suitable for adults only. The same conditions in children are treated with other medications.
When you order Gemfibrozil and start the therapy, you should know that you will need to systematically monitor the level of lipids in the blood. If the expected lowering of lipids isn’t achieved within three months of uninterrupted therapy, the therapy must be discontinued and other medicines considered. In the process of treatment and after its termination, it is necessary to observe a special low cholesterol diet. In long-term treatment, systematic monitoring of the peripheral blood pattern and liver function parameters is required (with a significant deviation of functional "liver" samples from the norm, the treatment is suspended until normalization). In case of missing the next dose, it is necessary to take it as soon as possible, but not to double if the time of the next dose has come. If muscle pain occurs, the presence of myositis should be excluded (including the definition of creatine kinase). In case of its detection, treatment is canceled. If cholelithiasis is detected, treatment is stopped.
Where to buy Lopid?
Naturally, you can get the medication from a regular drugstore but if you want to get it cheaper, you can order Generic Gemfibrozil from this web page and enjoy the same effect for several times less money.
Our online pharmacy ships internationally within a week to up to a month depending on the type of delivery you choose.
Our doctor prescribes Gemfibrozil online for free, and there is no doctor’s consultation fee.
All orders of Gemfibrozil arrive in discrete unmarked parcels. We leave the shipment description blank.