Diamox (Acetazolamide 250 mg)
Generic Diamox (Acetazolamide 250 mg) guide:
What is Diamox?
The medication you know under the trade name Diamox is based on the active substance called Acetazolamide. It was first introduced in the medical use in 1952. Currently, the medication is available also in a form of generics, i.e. the same substance and formula simply made by another company and therefore sold under a different trademark. It means that when you are prescribed to buy Diamox, you can save purchasing a generic medication instead.
The preparation is a diuretic, antiepileptic, antiglaucomal, and inhibiting carbonic anhydrase agent that is used for swelling caused by various reasons, glaucoma, some forms of epilepsy, and so on.
The medication enhances diuresis (i.e. urination) through the deletion of a certain type of electrolytes that doesn’t influence the general electrolyte balance in the body. The principle of this action is the suppression of carbonate dehydratase enzyme that plays a crucial role in the transportation of ions and preservation of ionic equilibrium of the organism. Suppressing the carbonate dehydratase in the convoluted tubule of the nephron, the preparation increases washing out of sodium and potassium with urine, but it does not impact the washing out of chlorine. It also alkalinizes the urine. The suppression of the carbonate dehydratase enzyme of the ciliated body leads to a diminished secretion of aqueous humor and the lowering of intraocular pressure. In the brain, it results in the anticonvulsant activity of the medication. Besides, it diminishes the production of cerebrospinal fluid and intracranial pressure. The continuance of the medication’s effect is up to twelve hours.
When taken orally, the medication is well-absorbed from the stomach. The maximum level in the organism of the active substance is achieved in two hours. The active agent penetrates placenta and the breast milk. It doesn’t transform and is excreted in urine in an unchanged form.
When the medication is used for a long period of time, it is important to regularly monitor the level o electrolytes in the blood as well as the peripheral blood condition.
When Acetazolamide-based preparation is taken in the dosages above the recommended, it can lead to the contrary effect – instead of enhancing diuresis it will diminish it and cause sleepiness and/or paresthesia. Nevertheless, in certain conditions, it is still used in higher doses along with other diuretics to ensure the certain diuretic action in completely refractory heart failure.
The preparation should not be used by people who drive every day or whose work requires attention focus.
Can you buy Generic Diamox to replace the branded medication in the therapy?
When your physician or other healthcare specialist appoints you the therapy with the branded drug Diamox, you can without any hesitation buy Generic Diamox instead. The thing is that the same medication can be and is produced by different pharmaceutical firms. The formula of the medication is known for a long time and is no longer protected by a copyright so it is absolutely legal for different drug makers to use the same formula and market the same medications. However, they are not all named the same. It is impossible for different companies to use the same trademark. So how would you know if you purchase the right medication? It is easily detected if you look at the name of the active substance on the box of pills when you get the pills. In the case with this preparation, the active agent name is Acetazolamide.
As for why people opt for generic versions of the drug, there is only one reason – they are cheaper. Fortunately, these medications are not inferior to the branded drug. They are cheaper because they are less promoted and their makers didn’t invent the chemical formula themselves. Considering that the cost of research had paid off multiple times since the branded medication had entered the market, it is safe to say that when you purchase a branded mediation you pay extra money for its promotion only and not for the better quality.
When is Acetazolamide (Diamox) indicated to be used?
The medications based on Acetazolamide are indicated for the therapy of glaucoma, including open-angle glaucoma, secondary glaucoma, and closed-angle glaucoma, as well as a short-term preoperative treatment to reduce intraocular pressure. The medications are also used for epilepsy in children manifested in large seizures and small seizures and in mixed forms in combination with anticonvulsants; edema associated with pulmonary heart disease or caused by medications; altitude sickness (to shorten the time of acclimatization).
Even if you have any of these conditions as your diagnosis, please make sure to get a consultation with a specialist before you buy Acetazolamide and start the therapy.
For whom the medication is contraindicated?
The medication is prohibited to be taken by people allergic to it and other sulfonamide medications, in hyponatremia, hypokalemia, adrenal insufficiency, renal and/or hepatic insufficiency, cirrhosis, urolithiasis (hypercalciuria), hyperchloremic acidosis, chronic decompensated closed-angle glaucoma (for prolonged therapy), diabetes, uremia, and during breastfeeding.
In addition, it is not recommended to be used or should be used cautiously in pulmonary embolism, emphysema (possibly increased acidosis), and during pregnancy.
What adverse effects can be triggered by the medication use?
The possible negative effects from the medication use are sleepiness, hearing impairment/noise in the ears, taste violation, vision impairment, disorientation, paresthesia, convulsions, lack of appetite, nausea, vomiting, diarrhea, liver failure, metabolic acidosis and electrolyte imbalance, hives, hypersensitivity to light, polyuria, hematuria, and glucosuria.
In case a patient has hypersensitivity to sulfonamide medications, there is a chance of severe adverse reactions development such as anaphylaxis, fever, rash (including multiform exudative erythema, toxic epidermal necrolysis, etc.), crystalluria, kidney stones, bone marrow suppression, thrombocytopenic purpura, anemia, leukopenia, pancytopenia, and agranulocytosis.
In case any skin side effects occur or the changes in the blood are noticed during the tests, the medication use must be stopped immediately.
Before you buy Generic Acetazolamide, talk to your doctor about what other adverse reactions must make you discontinue the therapy and inform your healthcare provider.
Most notable interactions with other substances
The diuretic effect can be enhanced by the use of theophylline and can be weakened by acid-forming diuretics.
The medication enhances osteomalacia (insufficient mineralization of bone tissue) manifestations caused by reception of antiepileptic drugs.
Simultaneous use of this diuretic with preparations of digitalis, carbamazepine, ephedrine, nondepolarizing muscle relaxants, salicylates, elevates the risk of these drugs’ toxic effects on the body.
It is important to render caution if you take order Diamox and plan to use it with acetylsalicylic acid (in high doses) due to the possibility of developing anorexia, tachypnea, lethargic state, and even a coma with the possible death.
Diamox overdose and treatment
To date, there are no data on the overdose of the medication. The possible symptoms of an overdose are the enhanced adverse reactions from the medication use. If they develop, a patient needs symptom-oriented and sustaining therapy.
How are Diamox tablets taken?
The tablets are taken orally. Here you can see the regular dosages recommended on the label but please make sure to receive the more precise and individual guidelines from your healthcare provider before you order Generic Diamox and start the therapy.
To reduce swelling, the recommended dosage is 250 mg taken one or two times a day. The therapy consists of five days with two-day interval and then the repeated course if needed.
To stop the onset of epileptic seizures in adults, the dosage is from 250 mg to 500 mg a day in a single intake. The medication should be taken for three days then a four-day break is made and then the course is repeated. Children aged from four months to one year should be administered 50 mg a day split into two intakes. Children aged from three to five years should be administered from 50 mg to 125 mg a day split into two intakes. Children older than five years should be administered from 125 mg to 250 mg a day in a single intake.
The therapy of chronic glaucoma is made with 125-500 mg of the drug taken from one to three times a day. The treatment course is five days. Also, for different forms of glaucoma, ophthalmic 0.2-0.3% solution of Acetazolamide with methylcellulose and hydroxyethylcellulose, or add beta-blockers can be used.
For the therapy of high altitude sickness, it is recommended to take the pills two-three times a day. The intake of the medication should be started one to two days before the climbing and be continued for two more days after you reach the goal altitude.
Where can you buy Diamox at a low price?
As we have previously discussed, if you do not want to pay extra money for the known name on the package, you should opt for a generic version of the medication. We offer you to order Acetazolamide without a prescription and with a delivery to your doorstep. Even paying for the delivery of this generic you will still save money on the visit to your doctor for a prescription and the pills themselves as the generic costs several times less money.
Shipping of Diamox
We offer you standard and express worldwide shipping. The standard one can take up to 25 days so if you need to get the pills sooner, opt for express shipping. If you don’t hurry to start the treatment but want to save to the maximum, you can order pills for $170 or more and we will ship your order for free via the standard mail.
Our doctor prescribes Acetazolamide online for free, and there is no doctor’s consultation fee.
All orders of Acetazolamide arrive in discrete unmarked parcels. We leave the shipment description blank.