The digestive tract of the human body is a complex system that works as a clock when healthy. It is crucial to understand that if one of the components of it falls out of normal work, all system the system crashes. The most frequent complaints when the digestive system is ill are heartburn, flatulence, burping, nausea, irregular stools, pain in the abdomen, and so on. Interestingly, the same symptoms can occur in different conditions. For instance, heartburn and accompanying symptoms can occur in gastritis, stomach ulcer, gastroesophageal reflux disease, and other dysfunctions. In order to get the right gastrointestinal drug and receive an effective treatment, it is important to establish the underlying reason for the existing symptoms with the help of special medical tests. In this article, we are going to review the most frequent gastrointestinal tract problems and illnesses, their diagnosis, and treatment methods available today.