More facts about Generic Clomid (Clomiphene 25 mg):
Generic Clomid (Clomiphene 25 mg) guide:
What is Generic Clomid?
You have probably heard about generic medications before. If not, here is a quick explanation of what Generic Clomid is.
Clomid is a patented name that is owned by a certain pharmaceutical company since 1967. The active substance of the medication that was given a name Clomiphene was developed in 1956 and the exclusive patent of the inventor has long expired. It means that the same medication’s formula can be used by different manufacturers of drugs. These drugs are collectively called Generic Clomiphene or Generic Clomid by the pharmacists from the countries where this brand name is the most widely known. These common names are not registered and cannot be because they comprise the registered names owned by some companies. Therefore, they are used only for convenience and all generics have their own registered trade names. But you don’t need to learn them if you wish to buy Clomid cheaper and therefore look for its generic. If you ask a pharmacist for Generic Clomid, he or she will know what drug to give you. And yes, generics are cheaper for multiple reasons. First of all, they are made on the basis of the formula that is developed by someone else, i.e. their manufacturers do not invest in the research and development. Secondly, such companies do not widely advertise their medications and restrict their registration and distribution of generics to certain regions without strong competition which also allows them to set the lower prices than the brand-name owners.
Clomiphene, the main ingredient of the drug, is an anti-estrogenic agent that selectively blocks the binding of estradiol to the receptors in the hypothalamus and ovaries, which leads to the promotion of ovulation due to the oppression of the reverse negative connection and enhanced production of gonadotropins. It is used for some cases of infertility.
If there any difference between the branded drug Clomid and the Generic Clomiphene?
There are differences: generics are cheaper and are sold without prescriptions in some countries. As for the difference in effect and harmlessness of the medicines, they are equal. Therefore, you can safely buy Generic Clomid or Clomiphene and use it as prescribed by your doctor.
When should you buy and use Generic Clomiphene?
The medication renders a potent effect on the reproductive system of a woman. Therefore, it must be used only if your doctor appoints you the therapy with the pills. Obviously, you can opt for Generic Clomiphene when your doctor recommends you the branded drug. The pills are mainly used to cope with infertility caused by certain imbalances. The cases in which the medication is appointed include:
- Anovulatory cycles
- Treatment of ovulation dysfunction caused by hypothalamus function deficiency
- Secondary amenorrhea of various causes
- Oligomenorrhea (rare periods)
- Dysfunctional uterine bleeding
- Non-cancerous galactorrhea
- Stein-Leventhal Syndrome (Polycystic ovary)
- Chiari-Frommel Syndrome
Besides, you doctor can decide that the medicine will be suitable for you even if you don’t have any of these conditions. But only a professional can appoint the therapy.
How is the effect of Clomiphene achieved?
The effect of the medicine is achieved through binding of the estrogens in the hypothalamus and ovaries. In low dosages, Clomiphene enhances the secretion of gonadotropin hormones and promotes ovulation. In a low level of endogenous estrogens in the body, Clomiphene has a gentle estrogenic effect, at a high level - antiestrogenic. Lowering the level of circulating estrogens, it stimulates the production of gonadotropins. In big dosages, it slows down the production of gonadotropins. The medicine has no gestagenic or androgenic activity.
When the pills are taken orally, the medicine is well absorbed from the gastrointestinal tract and is metabolized in the liver. Clomiphene is excreted in bile and feces.
How should the pills be taken?
Considering that the medication is a strong regulator of hormones level, it is important to consult your doctor to get individual recommendations on its use before you buy Clomiphene. However, the instruction provides the following general recommendations:
If the menstruations are preserved while there is no ovulation, it is recommended to start taking Clomiphene on the 5th day of the menstrual cycle and until the 10th day of the cycle in the dosage of 50 mg taken once a day. During this time, the reaction of the ovaries to the medication is constantly monitored. Usually, the ovulation occurs on the 10-15th day of the cycle.
If ovulation hadn’t occurred, the dosages of the medication for the next menstrual cycle are increased to 100 mg a day and the drug is taken using the same scheme, i.e. from the 5th to 10th day of the menstrual cycle. If the ovulation hadn’t occurred, the same course with 100 mg dosage a day can be repeated in the next menstrual cycle.
If the preparation had not been effective even after the 3 complete courses, the next therapy course can be prescribed not sooner than in 3 months. If even after the second complete three-month course the ovulation hadn’t occurred, repeated courses are not recommended.
The total dosage of the medication for the entire treatment course must not exceed 750 mg.
In the case of lack of menstruations, Generic Clomid is taken for 5 days in the dosage of 50 mg.
For the treatment of male infertility associated with oligospermia, the medication is prescribed in the dosage of 50 mg once a day for 6 weeks.
People with kidney problems do not require the lowering of the dosages. However, the function of kidneys should be monitored regularly during the therapy.
People with moderate to severe liver dysfunction must not use the medication.
Pregnancy and breastfeeding
The medication is strictly contraindicated during this time.
Contraindications for Generic Clomid therapy
You must not buy Generic Clomiphene if you have an allergy or intolerance to the main active substance or additional components of the pills, are pregnant or breastfeeding, suffer from severe liver disease, ovarian cyst (the medicine increases the risk of rupture of the cyst), visual impairment, history of uterine bleeding, cancer or decreased pituitary function.
Possible adverse reactions during the therapy
Usually, adverse reactions develop if the drug is prescribed in high dosages. The most common ones are headache, nausea, asthenia (general weakness), dizziness, anxiety, depression, abdominal pain, vomiting, hot flashes, and weight gain.
In some cases, the ovaries sizes increase up to 5 - 8 cm. Thus, it is important to monitor basal temperature and ovarian size via ultrasound is necessary during the therapy.
In extremely rare cases, Clomiphene can cause itching dermatitis, pain in the chest, or violation of urination.
You should also know before you order Clomid that the use of the medicine increases the likelihood of multiple birth, i.e. you can have twins, triplets, and so on.
Interaction with other preparations
The instruction says that the medication doesn’t negatively interact with any other drugs. However, we still advise you to inform your doctor about any medicines that you use or plan to use at a time of the therapy.
The typical symptoms of an overdose with the preparation include nausea, vomiting, flushing, and pains in the abdomen. There is no specific antidote for the medication. Therefore, if you overdose you would need a symptomatic treatment, i.e. therapy aimed to reduce the side effects of the increased drug dosage.
Where can you buy Clomid to save on the therapy?
If you live in the country where all medicines are expensive and sold only with a prescription, you can significantly save if you order Generic Clomid from our online drugstore. Not only our prices are lower than at the regular drugstores but we also sell the medicines without Rx what can save you money on the visits to your doctor.
Generic Ceclor shipping
We ship all medications including Generic Clomid to all countries of the world. We offer standard and express shipping but the time your medicine arrives and the cost of delivery depends on the region where you live. If you want to save on delivery, you can order pills in total for 170 Dollars or its equivalent in another currency and our online drugstore will ship your order free of charge. To find out more about our other bonuses and discounts, please read the FAQ section.
Our doctor prescribes Clomiphene online for free, and there is no doctor’s consultation fee.
All orders of Clomiphene arrive in discrete unmarked parcels. We leave the shipment description blank.